2 comments

  • neom 32 minutes ago
  • agnosticmantis 58 minutes ago
    In mice.
    • derektank 19 minutes ago
      Humans have the same protein. Knock out studies in mice have historically been very informative about human biology (with some exceptions). That’s very different from drug studies, where the molecules not only have to have the same effect in the model species, but also all off target effects have to be similar. That’s a higher barrier to clear and why mice studies of pharmaceutical interventions should (and do) face higher scrutiny.